Yes, you can wear your dentures at night but it is preferred that they be removed. You should remove your dentures at night and this will give your gums and bone a chance to relax from the pressure of the denture during the day. If you need to wear your dentures for social reasons or to prevent your jaws from over closing, you should find time during the day to properly clean your mouth and your prostheses. You should never wear your dentures 24 hours a day without preforming proper oral hygiene. Dentures should be cleaned at night and stored in water during the night.